Natsume, a chipper high school girl, was born and raised on Earth. She has longed to visit her parents' homeland, the "Land of the Fantastic Beasts". The Land of the Fantastic Beasts" is said to be a land of beautiful and mysterious monsters, various countries, and different cultures. With great anticipation, Natsume sets off for the land of the fantastic beasts, which opens only once every 12 years. Meanwhile, in the Land of the Beast, Natsume's grandfather, Archduke Seguro, who was worried about Natsume's journey and foresaw danger ahead, ordered Tite and Nebulosa of the Dragon Knights of Fillone to watch over Natsume in secret. However, just as Natsume was about to return to Earth after enjoying sightseeing in the rich southern country of Lavendula, the army of the Bomareo nation, led by King Atreides, suddenly invaded. If they do not escape that day, the door to Earth will be closed...! A mysterious and beautiful world of fantastic beasts spun out of unbridled imagination...a breathtaking and thrilling development.