2 years after the end of Ben 10 Ominiverse, Ben and his friends (Rook, Kevin, Gwen, Zed and Kai) travel around the universe to explore it, but in the middle of their trip they ended up coming across the Galord ship, a villain who hunts different races by dimensions to make his own experiments. During all of this Ben's Ominitrix goes into recalibration mode and '' unlocks '' 10 new aliens. Now our heroes travel across the world to destroy a great threat from Galord; while Ben will have to learn to turn again with his new powers.