A first-year high-school boy, Kirifu Ishigami, who’s always gone with the flow, meets a homunculus girl named Homun in the clubroom of the Alchemy Club, a club that should have been disbanded. Homun, who doesn’t know what she wants to do, comes to rely on Kirifu, but he’s hassled by some rough classmates and lands in big trouble! Then, incredibly, Homun eats Kirifu and “alchemizes” him… A fresh new sensation!? The alchemy-style comedy begins☆