In this world, where interspecies interaction between humans and youkai has progressed, there are "half-demons" who still retain the characteristics of youkai. Kogami Shiro, a descendant of a wolf who attends Yamamoto Half-Demon Academy, a high school where half-demons gather, has a problem. He transforms into a wolf when he gets nervous! "Today I'm not going to turn into a wolf!!" Shiro vows, but when he's in front of a girl, he turns into a wolf in an instant. His classmate, Kabe Nurumi, offers to help Shiro. For Kabe, a descendant of Nurikabe, Shiro's efforts to overcome his weaknesses seem to have stumbled over a "sexual 'wall'"...?