Reiji Ooyama has always lived in the shadow of his father, an exceptional fighter. So he decided to go and train around the world in the hope of surpassing him. But on his return to Japan, he learns of his father's death. In his misfortune, he meets Annie Hamilton, another fighter, intrigued by the mark on his neck. A strange destiny seems to unite them, but they are not alone. They are soon joined by Keith Wayne, and the three of them set off on an adventure to unravel the mystery surrounding the mark. Targeted by warriors with strange abilities, using their fists to fight their way through, they discover the existence of the Gôketsuji clan and the identity of a terrible enemy. Friendships, rivalries and colossal battles are the watchwords of this story!